According to the Global Islamic Economy Report, the halal industry is no longer a fleeting phenomenon, but rather involves a global value of $3 trillion...
BPOM - A Brief Overview of Cosmetic Testing Items
2025-12-31
A. Determination of microbial contamination in cosmetics
A.1 Determination of mold and yeast counts and total colony count in cosmetics
principle:
This method involves counting molds and yeasts on selective agar medium.
If it is estimated that the sample may inhibit microbial growth, the sample must be neutralized in order to detect live microorganisms, and the neutralization procedure must be validated.
A.2 Cosmetic preservative effectiveness testing
principle:
Uncontaminated products were challenge-tested using established standard microorganisms, and then the inoculated products were stored at a specified temperature. The number of surviving standard microorganisms in the test products was counted using plate count at specified time intervals.
B.Analytical methods for determining the pollution levels of heavy metals (arsenic, cadmium, lead, mercury) in cosmetics
principle:
Samples were digested using wet digestion, dry digestion, or high-pressure microwave digestion (HPMD), and the contents of heavy metals such as arsenic (As), cadmium (Cd), lead (Pb), and mercury (Hg) were determined using a graphite furnace atomic absorption spectrophotometer (GF-AAS) and a flow cytometry system-atomic absorption spectrophotometer (FIAS-AAS).
C. Identification of retinoids in cosmetics
principle:
Retinic acid was identified using thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC).
D. Identification of prohibited pigments in cosmetics
Identification of prohibited pigments by thin-layer chromatography (TLC)
principle:
Prohibited coloring ingredients in cosmetics were extracted and identified using thin-layer chromatography (TLC).
Identification of prohibited pigments by high performance liquid chromatography (HPLC)
principle:
Identification of prohibited colorants in cosmetics using reversed-phase liquid chromatography combined with visible light detection.
AND.Identification and determination of hydroquinone content in cosmetics
Thin-layer chromatography (TLC)TLC）
principle:
Identification of hydroquinone by thin-layer chromatography
KCKTLaw
principle:
passUVInverted detectionHPLCMethods for identifying hydroquinone.
F.Identification of corticosteroid compounds in cosmetics
Thin-layer chromatography (TLC)TLC）
principle:
Thin-layer chromatography (TLC)TLCExtract and identify corticosteroid compounds in the samples.
HPLCLaw
principle:
By inversionHPLCThe glucocorticoid compounds in the samples were extracted and identified using ultraviolet detection.
G.Identification of several preservatives used in cosmetics
Thin-layer chromatography (TLC)TLC)
principle:
passKLTPreservatives were extracted from the samples and identified.
HPLCLaw
principle:
Preservatives were extracted from the sample, identified, and analyzed using a reverse-phase chromatography method.HPLCIts content was determined by a method using isopropyl...4-Hydroxybenzoate or benzophenone were used as internal standards.