EU Animal Research Regulations

EU Animal Research Regulations Animal research in the European Union (EU) is governed by Directive 2010/63/EU on the protection of animals used for scientific purposes . The ultimate aim of the directive is to replace all animal research with non-animal research methods, such as organoids or computer simulation. The directive harmonizes animal research legislation across the EU to ensure high standards of animal welfare and scientific research. It was transposed into the national law of each EU member state in 2013. Member states that had adopted stricter measures to protect research animals before the directive came into force may retain them, provided they do not hinder scientific cooperation and trade within the EU. Animals may be used in research in the EU only where there is a compelling scientific justification, when the expected benefits of the research outweigh the potential risks in terms of animal suffering, and when the scientific objectives cannot be achieved using non-animal alternatives. Only projects that meet these requirements can be authorized. The directive sets out legal requirements to implement the 3R principles of replacement, reduction and refinement: where possible, replacing animals with non-animal methods; reducing the number of animals used to a minimum while still obtaining scientifically valid results; and refining practices to reduce any possible pain, suffering, distress or lasting harm to animals. In the EU, animals are used for a limited range of research purposes, including basic research, applied research into human and animal diseases and treatments, the conservation of species and the environment, and education and training. Since 2013, the EU-wide ban on animal testing for cosmetic purposes has been complete.